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Fertil Steril. 2016 Sep 15;106(4):905-29. doi: 10.1016/j.fertnstert.2016.07.1076. Epub 2016 Aug 9.

Environmental influences on reproductive health: the importance of chemical exposures.

Author information

1
Program on Reproductive Health and the Environment, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, California; Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, California.
2
Program on Reproductive Health and the Environment, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, California.
3
Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, California.
4
Program on Reproductive Health and the Environment, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, California. Electronic address: Tracey.Woodruff@ucsf.edu.

Abstract

Chemical exposures during pregnancy can have a profound and life-long impact on human health. Because of the omnipresence of chemicals in our daily life, there is continuous contact with chemicals in food, water, air, and consumer products. Consequently, human biomonitoring studies show that pregnant women around the globe are exposed to a variety of chemicals. In this review we provide a summary of current data on maternal and fetal exposure, as well as health consequences from these exposures. We review several chemical classes, including polychlorinated biphenyls, perfluoroalkyl substances, polybrominated diphenyl ethers, phenols, phthalates, pesticides, and metals. Additionally, we discuss environmental disparities and vulnerable populations, and future research directions. We conclude by providing some recommendations for prevention of chemical exposure and its adverse reproductive health consequences.

KEYWORDS:

Chemical; environmental chemical; environmental exposure; pregnancy; reproductive health

PMID:
27513554
PMCID:
PMC5158104
DOI:
10.1016/j.fertnstert.2016.07.1076
[Indexed for MEDLINE]
Free PMC Article

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