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Springerplus. 2016 Jul 26;5(1):1184. doi: 10.1186/s40064-016-2840-y. eCollection 2016.

Novel technique of vulvo-vaginal rejuvenation by lipofilling and injection of combined platelet-rich-plasma and hyaluronic acid: a case-report.

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Department of Plastic, Reconstructive and Aesthetic Surgery, Henri Mondor Hospital, 51 Avenue du Maréchal de Lattre de Tassigny, 94010 Créteil, France.



To describe a new surgical procedure and its results: the vulvo-vaginal rejuvenation by lipofilling and an injection of combined platelet-rich-plasma (PRP) and hyaluronic acid (HA). Sexual life for women is affected by the effect of aging and by post partum traumatism. There are no standard non-invasive treatments to offer to improve the trophic and dimensional alterations of the vulvo-vaginal area. The surgical procedure consists in a vaginoplasty by lipofilling of the posterior vaginal wall far from the vascular axes and with an injection of an injection of combined PRP and HA subcutaneously in the perineum. To illustrate the technique and evaluate its results, we present the case of a 39 year-old-female with history of episiotomy presented that vaginal laxity resistant to physical therapy. To assess the results regarding the sexual quality of life we used the modified Stabbatsberg self-rating scale.


There were no intra-operative complications with this simple procedure. During follow-up we observed an improvement in the modified Stabbatsberg scale and a vulvo-perineal rejuvenation by improving the vaginal trophicity and restoring a normal vaginal caliber. No post-operative complications occurred.


Vulvo-vaginal rejuvenation lipofilling and an injection of combined platelet-rich-plasma and hyaluronic acid is a minimally invasive technique that is safe and easy to perform. Further studies are necessary to assess more thoroughly the effectiveness and safety of this procedure and assess medium and long term results.


Hyaluronic acid; Lipofilling; Perineal rejuvenation; Platelet-rich plasma; Sexual dysfunction; Vaginoplasty

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