Format

Send to

Choose Destination
Curr Urol Rep. 2016 Oct;17(10):70. doi: 10.1007/s11934-016-0627-x.

Genetics of Male Infertility.

Author information

1
Center for Male Reproductive Medicine and Microsurgery, Department of Urology and Institute of Reproductive Medicine, Weill Cornell Medical College, New York, NY, USA.
2
Center for Male Reproductive Medicine and Microsurgery, Department of Urology and Institute of Reproductive Medicine, Weill Cornell Medical College, New York, NY, USA. mgoldst@med.cornell.edu.

Abstract

While 7 % of the men are infertile, currently, a genetic etiology is identified in less than 25 % of those men, and 30 % of the infertile men lack a definitive diagnosis, falling in the "idiopathic infertility" category. Advances in genetics and epigenetics have led to several proposed mechanisms for male infertility. These advances may result in new diagnostic tools, treatment approaches, and better counseling with regard to treatment options and prognosis. In this review, we focus on clinical aspects of male infertility and the role of genetics in elucidating etiologies and the potential of treatments.

KEYWORDS:

Epigenetics; Genetics; Male infertility; Reproduction

PMID:
27502429
DOI:
10.1007/s11934-016-0627-x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center