Objective: To study the relationship between renal failure and severe postoperative hypoxemia of patients received surgical procedure for Stanford A aortic dissection.
Methods: Clinical data of 411 consecutive patients from January 2014 to April 2015, who received surgical procedure for Stanford A aortic dissection in Department of Cardiovascular Surgery of Beijing Anzhen Hospital, were collected retrospectively. The appearance of severe postoperative hypoxemia was recorded in all the cases. All the data about potential prognostic factors was put into the database and analyzed by univariate and multivariate Logistic regression respectively.
Results: Severe postoperative hypoxemia (PO2/FiO2<100 mmHg, 1 mmHg=0.133 kPa) happened on 69 cases within 48 hours after procedures, with the incidence rate of 17.1%. Both univariate and multivariate Logistic regression indicated the influence that preoperative creatinine clearance rate had on severe postoperative hypoxemia showed no statistical significance. However, the influence of preoperative serum creatinine showed statistical significance (OR=1.009, 95%CI: 1.000 to 1.018, P=0.048).
Conclusions: The preoperative creatinine clearance rate of patients has no direct relationship with severe postoperative hypoxemia. But the preoperative serum creatinine could be regarded as an independent predictor of severe postoperative hypoxemia.