Hematopoietic Lineage Diversification, Simplified

Roy Drissen; Claus Nerlov

doi:10.1016/j.stem.2016.07.010

Hematopoietic Lineage Diversification, Simplified

Cell Stem Cell. 2016 Aug 4;19(2):148-150. doi: 10.1016/j.stem.2016.07.010.

Authors

Roy Drissen¹, Claus Nerlov²

Affiliations

¹ MRC Molecular Hematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
² MRC Molecular Hematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK. Electronic address: claus.nerlov@imm.ox.ac.uk.

PMID: 27494670
DOI: 10.1016/j.stem.2016.07.010

Abstract

Hematopoiesis is a complex process that requires a high degree of transcriptional diversification during lineage commitment and differentiation. de Graaf et al. (2016) have now generated a comprehensive gene expression dataset that allows cell-type-specific genes as well as associated transcription factor expression patterns to be readily identified.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Cell Differentiation
Cell Lineage / genetics*
Hematopoiesis / genetics
Hematopoietic Stem Cells*
Humans
Transcription Factors / genetics

Substances

Transcription Factors

Abstract

Publication types

MeSH terms

Substances

Grants and funding