Functional acute liver failure after treatment with pegylated asparaginase in a patient with acute lymphoblastic leukemia: potential impact of plasmapheresis

Ann Hematol. 2016 Oct;95(11):1899-901. doi: 10.1007/s00277-016-2773-0. Epub 2016 Aug 4.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Asparaginase / administration & dosage
  • Asparaginase / adverse effects*
  • Asparaginase / pharmacokinetics
  • Combined Modality Therapy
  • Humans
  • Hyperbilirubinemia / chemically induced
  • Hypoalbuminemia / chemically induced
  • Liver Failure / blood
  • Liver Failure / chemically induced*
  • Liver Failure / therapy
  • Male
  • Plasmapheresis
  • Polyethylene Glycols / administration & dosage
  • Polyethylene Glycols / adverse effects*
  • Polyethylene Glycols / pharmacokinetics
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Remission Induction

Substances

  • Polyethylene Glycols
  • pegaspargase
  • Asparaginase