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BMC Musculoskelet Disord. 2016 Aug 2;17:320. doi: 10.1186/s12891-016-1179-4.

Factors associated with diagnostic stage of hip osteoarthritis due to acetabular dysplasia among Japanese female patients: a cross-sectional study.

Author information

1
Department of Public Health, Graduate School of Medicine, Osaka City University, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan. satop@med.osaka-cu.ac.jp.
2
Department of Orthopaedic Surgery, Kyushu Rosai Hospital of Japan Labor Health and Welfare Organization, Kitakyushu, Japan.
3
Department of Public Health, Graduate School of Medicine, Osaka City University, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
4
Orthopaedic Division, Nakajo Central Hospital, Niigata, Japan.
5
Department of Orthopedic Surgery, School of Medicine, Kitasato University, Sagamihara, Japan.
6
Hakutokai Takao Hospital, Hachioji, Japan.
7
Department of Orthopaedic Surgery, Kanazawa Medical University, Uchinada, Japan.
8
Orthopaedic Division, Mitsuwadai General Hospital, Chiba, Japan.
9
Department of Orthopaedic Surgery, Graduate School of Medicine, Nagasaki University, Nagasaki, Japan.
10
Department of Orthopaedic Surgery, Japan Community Health Care Organization Yugawara Hospital, Kanagawa, Japan.
11
Department of Orthopaedic Surgery, Fujita Health University School of Medicine, Toyoake, Japan.
12
Department of Orthopaedic Surgery, Hiroshima Prefectural Rehabilitation Center, Hiroshima, Japan.
13
Department of Orthopaedic Surgery, Asahikawa Medical University, Asahikawa, Japan.
14
Department of Bone and Joint Surgery, Seirei Hamamatsu General Hospital, Hamamatsu, Japan.
15
Department of Orthopaedic Surgery, Okinawa Red Cross Hospital, Naha, Japan.
16
Tohoku Hip Joint Center, Matuda Hospital, Sendai, Japan.
17
Department of Orthopedic Surgery, Saiseikai Nakatsu Hospital, Osaka, Japan.
18
Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka City University, Osaka, Japan.
19
College of Healthcare Management, Miyama, Japan.

Abstract

BACKGROUND:

In Japan, the majority of hip osteoarthritis (OA) was caused by acetabular dysplasia, and about 90 % of patients were female. The present study focused on Japanese female patients with hip OA due to acetabular dysplasia, and examined the associated factors with OA staging at diagnosis, in special reference to body weight.

METHODS:

Study subjects were 336 Japanese women who were newly diagnosed with hip OA caused by acetabular dysplasia at 15 hospitals in 2008. The self-administered questionnaire elicited patients' body weight at age 20 and at OA diagnosis. Four ranked OA staging according to radiographic findings of the hip joint (pre-OA, initial stage, advanced stage or terminal stage) was regarded as the outcome index. Proportional odds models in logistic regression were used to calculate odds ratios (ORs) and 95 % confidence intervals (CIs) for severer stage of OA.

RESULTS:

At diagnosis, 45 % of patients suffered from terminal stage of OA, whereas 13 % and 14 % were categorized into pre-OA and initial stage, respectively. After adjustment for potential confounders, weight gain since age 20 revealed the increased ORs for severer OA stage at diagnosis (OR 2.02; 95 % CI, 1.07-3.80). Other significant characteristics were age (67+ vs. 20-49 years, OR 12.4), lower education (junior high school vs. junior college or higher, OR 4.00), parity (OR 2.19), lower acetabular head index (<60.0 vs. 71.1+, OR 2.36), and longer duration since symptom onset (6.0+ vs. <1.0 year, OR 2.94).

CONCLUSIONS:

Weight gain since age 20 might be involved in mechanisms of OA development, which is independent of age or severity of acetabular dysplasia.

KEYWORDS:

Anthropometric factors; Body weight; Disease severity; Epidemiology; Hip osteoarthritis

PMID:
27484820
PMCID:
PMC4971752
DOI:
10.1186/s12891-016-1179-4
[Indexed for MEDLINE]
Free PMC Article

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