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J Clin Exp Ophthalmol. 2016 Jun;7(3). pii: 570. Epub 2016 Jun 27.

Multimodal Imaging of the White Dot Syndromes and Related Diseases.

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National Eye Institute, National Institutes of Health, Bethesda, USA.


The white dot syndromes encompass a group of rare posterior uveitis conditions that are characterized by outer retinal and/or choroidal hypopigmented lesions that are thought to be inflammatory in nature. The size, shape, and location of lesions in the fundus aid in differentiating these conditions. Multimodal imaging, including modalities such as fundus autofluorescence, optical coherence tomography, fluorescein angiography, and indocyanine green angiography, among others, has become integral in diagnosing and monitoring many of the white dot syndromes. Furthermore, multimodal imaging modalities have provided insights into the pathogenesis and exact sites within the retina and choroid affected by white dot syndromes.


Multimodal imaging; Uveitis; White dot syndromes


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