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Br J Psychiatry. 2016 Aug;209(2):93-4. doi: 10.1192/bjp.bp.116.185405.

Schizophrenia genetics moves into the light.

Author information

1
David Curtis, MD, PhD, FRCPsych, UCL Genetics Institute, UCL, and Centre for Psychiatry, Barts and the London School of Medicine and Dentistry, Darwin Building, Gower Street, London WC1E 6BT, UK. Email: d.curtis@ucl.ac.uk.

Abstract

Two recent reports convincingly demonstrate that the risk of schizophrenia is influenced by common variation of C4, which codes for complement component 4, and by rare, disruptive mutations of SETD1A, which codes for a histone methylase. These important results open the way for major advances in our understanding of the fundamental biological processes leading to disease.

PMID:
27482034
DOI:
10.1192/bjp.bp.116.185405
[Indexed for MEDLINE]

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