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Evid Based Complement Alternat Med. 2016;2016:8469024. doi: 10.1155/2016/8469024. Epub 2016 Jul 11.

Spectral Analysis of Chinese Medicinal Herbs Based on Delayed Luminescence.

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Shandong Medicinal Biotechnology Center, Key Laboratory for Biotech-Drugs, Ministry of Health, Shandong Academy of Medical Sciences, Jinan, Shandong 250062, China.
Shandong Center for Disease Control and Prevention, Jinan, Shandong 250014, China.
Department of Basic Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China.
Shandong Academy of Traditional Chinese Medicine, Jinan, Shandong 250014, China.
Sino-Dutch Centre for Preventive and Personalized Medicine/Centre for Photonics of Living Systems, Leiden University, 2300 RA Leiden, Netherlands.


Traditional Chinese medicine (TCM) plays a critical role in healthcare; however, it lacks scientific evidence to support the multidimensional therapeutic effects. These effects are based on experience, and, to date, there is no advanced tool to evaluate these experience based effects. In the current study, Chinese herbal materials classified with different cold and heat therapeutic properties, based on Chinese medicine principles, were investigated using spectral distribution, as well as the decay probability distribution based on delayed luminescence (DL). A detection system based on ultraweak biophoton emission was developed to determine the DL decay kinetics of the cold and heat properties of Chinese herbal materials. We constructed a mathematical model to fit the experimental data and characterize the properties of Chinese medicinal herbs with different parameters. The results demonstrated that this method has good reproducibility. Moreover, there is a significant difference (p < 0.05) in the spectral distribution and the decay probability distribution of Chinese herbal materials with cold and heat properties. This approach takes advantage of the comprehensive nature of DL compared with more reductionist approaches and is more consistent with TCM principles, in which the core comprises holistic views.

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