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J Lipid Res. 2016 Oct;57(10):1771-1777. Epub 2016 Jul 29.

The early years of lipoprotein research: from discovery to clinical application.

Author information

1
Children's Hospital Oakland Research Institute, Oakland, CA 94609-1673 psiri@chori.org rkrauss@chori.org.

Abstract

This review outlines major milestones in the first four decades of lipoprotein research beginning with their discovery nearly 90 years ago. It focuses on the contributions of some of the key investigators during this era, and findings that set the stage for widespread clinical implementation of lipoprotein testing for evaluation and management of CVD risk.

KEYWORDS:

atherosclerosis; cholesterol; history; low density lipoprotein

PMID:
27474223
PMCID:
PMC5036374
DOI:
10.1194/jlr.R069575
[Indexed for MEDLINE]
Free PMC Article

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