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Int J Legal Med. 2016 Nov;130(6):1505-1507. Epub 2016 Jul 28.

Genetic variation of 17 STR loci in a Mexican Mestizo population from Mexico City.

Author information

1
Laboratory of Genetic Identification, Department of Legal Medicine, Toxicology and Physical Anthropology, Universidad de Granada, Avda. de la Investigación 11, 18016, Granada, Spain. msaiz@ugr.es.
2
Anigen Center of Studies and Investigations, Municipio Libre 366, Col. Sta. Cruz Atoyac Del., C.P. 03310, Benito Juárez, Mexico.
3
Laboratory of Genetic Identification, Department of Legal Medicine, Toxicology and Physical Anthropology, Universidad de Granada, Avda. de la Investigación 11, 18016, Granada, Spain.
4
Pfizer-University of Granada-Junta de Andalucia Centre for Genomics and Oncological GENYO, Biomedical Research Centre, Avda. del Conocimiento s/n, 18100, Armilla, Granada, Spain.

Abstract

Genetic data from 17 autosomal short tandem repeat (STR) loci found in the Powerplex® ESX 17 System (Promega, Madison, WI, USA) was evaluated in 162 unrelated Mexican Mestizo individuals from Mexico City. Allele frequencies and forensic parameters were estimated for the 17 STRs. All loci analyzed were in Hardy-Weinberg equilibrium in the studied population and showed not any signs of linkage between loci. The combined power of discrimination and the power of exclusion for the 16 aSTRs studied were 1-2.56409·10-19 and 99.999938 %, respectively. Genetic distances reveal a close relationship within different populations of Mexican Mestizos. The obtained data might be useful for population genetics research and for individual identification and paternity testing in forensic science.

KEYWORDS:

Mexican Mestizos; Mexico City; Powerplex® ESX 17 System; STRs

PMID:
27470318
DOI:
10.1007/s00414-016-1423-3
[Indexed for MEDLINE]

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