Polyoxygenated ursane and oleanane triterpenes from Siphonodon celastrineus

Phytochemistry. 2016 Sep:129:58-67. doi: 10.1016/j.phytochem.2016.07.006. Epub 2016 Jul 25.

Abstract

Twenty polyoxygenated triterpenes, including nineteen ursanes and one oleanane, were characterized from the stem material of Siphonodon celastrineus (Celastraceae) through the application of spectroscopic techniques and chemical transformation. Three of the ursane-type triterpenoids possessed the rare 13,27-cyclopropane ring skeleton.

Keywords: 13,27-Cyclopropane ring triterpenes; Celastraceae; Cytotoxicity; Oleanane; Polyoxygenated pentacyclic triterpenes; Siphonodon celastrineus; Ursane.

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Celastraceae / chemistry*
  • Drug Screening Assays, Antitumor
  • Molecular Structure
  • Oleanolic Acid / analogs & derivatives
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification*
  • Oleanolic Acid / pharmacology
  • Plant Stems / chemistry
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*
  • Triterpenes / pharmacology

Substances

  • Antineoplastic Agents, Phytogenic
  • Triterpenes
  • oleanane
  • ursane
  • Oleanolic Acid