Abstract
Twenty polyoxygenated triterpenes, including nineteen ursanes and one oleanane, were characterized from the stem material of Siphonodon celastrineus (Celastraceae) through the application of spectroscopic techniques and chemical transformation. Three of the ursane-type triterpenoids possessed the rare 13,27-cyclopropane ring skeleton.
Keywords:
13,27-Cyclopropane ring triterpenes; Celastraceae; Cytotoxicity; Oleanane; Polyoxygenated pentacyclic triterpenes; Siphonodon celastrineus; Ursane.
Copyright © 2016 Elsevier Ltd. All rights reserved.
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Celastraceae / chemistry*
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Drug Screening Assays, Antitumor
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Molecular Structure
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Oleanolic Acid / analogs & derivatives
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Oleanolic Acid / chemistry
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Oleanolic Acid / isolation & purification*
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Oleanolic Acid / pharmacology
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Plant Stems / chemistry
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Triterpenes / chemistry
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Triterpenes / isolation & purification*
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Triterpenes / pharmacology
Substances
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Antineoplastic Agents, Phytogenic
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Triterpenes
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oleanane
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ursane
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Oleanolic Acid