Format

Send to

Choose Destination
Ann Pediatr Endocrinol Metab. 2016 Jun;21(2):99-104. doi: 10.6065/apem.2016.21.2.99. Epub 2016 Jun 30.

A successful treatment of hypercalcemia with zoledronic acid in a 15-year-old boy with acute lymphoblastic leukemia.

Author information

1
Department of Pediatrics, Catholic University of Daegu School of Medicine, Daegu, Korea.

Abstract

Severe hypercalcemia in children is a rare medical emergency. We present a case of a 15-year-old boy with hypercalcemia (total calcium level, 14.2 mg/dL) with a normal complete blood count, no circulating blasts in the peripheral blood film, and no other signs of acute lymphoblastic leukemia (ALL), including no signs of lymphadenopathy or hepatosplenomegaly. The hypercalcemia was successfully treated with zoledronic acid. As hypercalcemia can be the only presenting symptom of ALL in children, the diagnosis is often delayed. In children presenting with hypercalcemia, malignancies must be considered in the differential diagnosis.

KEYWORDS:

Hypercalcemia; Leukemia; Osteoclast activating factor

Supplemental Content

Full text links

Icon for Publishing M2Community Icon for PubMed Central
Loading ...
Support Center