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J Health Psychol. 2018 Sep;23(11):1452-1463. doi: 10.1177/1359105316659917. Epub 2016 Jul 24.

A global measure of sickness behaviour: Development of the Sickness Questionnaire.

Author information

1
1 Karolinska Institutet, Sweden.
2
2 Stockholm University, Sweden.
3
3 Karolinska University Hospital, Sweden.

Abstract

Symptoms after inflammatory activation, so-called sickness behaviour, overlap with trans-diagnostic complaints. As no self-report questionnaire to assess sickness behaviour exists, we aimed to develop such an instrument, the Sickness Questionnaire. Items responsive to experimentally induced inflammatory activation (randomized double-blind study endotoxin (0.6 ng/kg) versus placebo, n = 52) were selected and the statistical properties were examined in 172 primary care patients. A principal component analysis indicated a one-factor solution (Cronbach's alpha = .86). This 10-item scale correlated with depression ( β = .41, p < .001), anxiety ( β = .36, p < .001), self-rated health ( β = .28, p < .001) and a single item of feeling sick ( β = .55, p < .001). The results support the adequacy of Sickness Questionnaire as a brief assessment instrument of perceived sickness behaviour.

KEYWORDS:

Sickness Questionnaire; endotoxin; sickness behaviour; sickness response; validation

PMID:
27458105
DOI:
10.1177/1359105316659917

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