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J Infect Dis. 2016 Oct 15;214(8):1171-4. doi: 10.1093/infdis/jiw307. Epub 2016 Jul 24.

Unique Presentation of Orf Virus Infection in a Thermal-Burn Patient After Receiving an Autologous Skin Graft.

Author information

1
Poxvirus and Rabies Branch Epidemic Intelligence Service, Atlanta, Georgia.
2
Department of Dermatology, Bo Ali Sina Hospital, Hamedan.
3
Razi Dermatology Hospital, Tehran University of Medical Sciences, Tehran, Iran.
4
Department of Dermatology, New York University Medical Center, New York.
5
Poxvirus and Rabies Branch.
6
Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention.

Abstract

We describe a burn patient who developed skin lesions on her skin-graft harvest and skin-graft recipient (burn) sites. Orf virus infection was confirmed by a combination of diagnostic assays, including molecular tests, immunohistochemical analysis, pathologic analysis, and electron microscopy. DNA sequence analysis grouped this orf virus isolate among isolates from India. Although no definitive source of infection was determined from this case, this is the first reported case of orf virus infection in a skin graft harvest. Skin graft recipients with exposures to animals may be at risk for this viral infection.

KEYWORDS:

Orf virus; Parapoxvirus; skin graft; thermal burn

PMID:
27456708
PMCID:
PMC5663183
DOI:
10.1093/infdis/jiw307
[Indexed for MEDLINE]
Free PMC Article

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