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Gynecol Oncol Rep. 2016 May 31;17:72-4. doi: 10.1016/j.gore.2016.05.010. eCollection 2016 Aug.

Nonbacterial thrombotic endocarditis: A rare manifestation of gynecologic cancer.

Author information

1
Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Gynecologic Oncology, The Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08901,United States.
2
Department of Medicine, Division of Cardiovascular Disease and Hypertension, Rutgers Robert Wood Johnson Medical School, One Robert Wood Johnson Place, New Brunswick, NJ 08903, United States.

Abstract

•Nonbacterial thrombotic endocarditis (NBTE) is a rare complication of cancer.•NBTE may precede the diagnosis of an occult gynecologic malignancy.•Malignancy-induced NBTE must be considered in patients with unprovoked venous thromboembolism.•The most effective treatment is anticoagulation and treatment of the underlying cancer.

KEYWORDS:

Anticoagulation; Chemotherapy; Endocarditis; Endometrial cancer; Ovarian cancer; Valvular vegetations

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