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Neurosci Lett. 2016 Sep 6;630:247-253. doi: 10.1016/j.neulet.2016.07.033. Epub 2016 Jul 20.

Acute high-intensity exercise-induced cognitive enhancement and brain-derived neurotrophic factor in young, healthy adults.

Author information

1
Department of Kinesiology and Health Education, University of Texas at Austin, TX 78712, USA.
2
Department of Kinesiology, College of Nursing and Health Innovation, University of Texas at Arlington, TX 76019, USA.
3
Department of Kinesiology and Health Education, University of Texas at Austin, TX 78712, USA. Electronic address: dcastelli@utexas.edu.
4
Department of Communication Studies, University of Texas at Austin, TX 78712, USA.
5
Department of Curriculum & Instruction, University of Texas at Austin, TX 78712, USA.

Abstract

Acute exercise can positively impact cognition. The present study examined the effect of acute high-intensity aerobic exercise on prefrontal-dependent cognitive performance and brain-derived neurotrophic factor (BDNF). Fifty-eight young adults were randomly assigned to one of two experimental groups: (a) an acute bout of high-intensity exercise (n=29) or (b) a non-exercise control (n=29). Participants in the exercise group improved performance on inhibitory control in Stroop interference and on cognitive flexibility in Trail Making Test (TMT) Part-B compared with participants in the control group and increased BDNF immediately after exercise. There was a significant relationship between BDNF and TMT Part-B on the pre-post change following exercise. These findings provide support for the association between improved prefrontal-dependent cognitive performance and increased BDNF in response to acute exercise. We conclude that the changes in BDNF concentration may be partially responsible for prefrontal-dependent cognitive functioning following an acute bout of exercise.

KEYWORDS:

Aerobic exercise; Brain-derived neurotrophic factor; Cognition; Young adults

PMID:
27450438
DOI:
10.1016/j.neulet.2016.07.033
[Indexed for MEDLINE]

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