Send to

Choose Destination
Adv Skin Wound Care. 2016 Aug;29(8):349-55. doi: 10.1097/01.ASW.0000484666.83140.b0.

A Pilot Study of the Efficacy of Active Leptospermum Honey for the Treatment of Partial-Thickness Facial Burns.

Author information

Christina L. Duncan, PhD, is Associate Professor, Department of Psychology, West Virginia University, Morgantown, West Virginia, and is a Consulting Psychologist, West Penn Hospital Burn Center, Allegheny Health Network, Pittsburgh, Pennsylvania. Paul T. Enlow, MS, is a Graduate Research Assistant and Clinical Psychology Extern, Department of Psychology, West Virginia University. Margo M. Szabo, MS, is a Graduate Research Assistant, Department of Psychology, West Virginia University. Eric Tolchin, PA-C, is a Physician Assistant, Allegheny Health Network. Robert W. Kelly, MD, and Lourdes Castanon, MD, are Attending Physicians, Allegheny Health Network. Ariel M. Aballay, MD, is the Medical Director, WestPenn Hospital Burn Center, Allegheny Health Network.



Research suggests that active Leptospermum honey (ALH) improves outcomes in patients with partial-thickness burns by enhancing healing and reepithelialization rates, as well as by protecting against antibiotic-resistant microorganisms. This study assessed the effectiveness of ALH gel on healing time, bacterial growth, patient satisfaction, and cost of treatment.


Single-arm, prospective case series.


Seven patients (aged 7-64 years) with partial-thickness facial burns were recruited from a northeastern US burn center.


All patients cleansed their wounds daily with soap and water, after which they applied ALH gel.


Three physicians independently rated healing using wound photography and daily tests for the presence of exudate. Wound cultures on days 1 and 7 (±2 days) assessed bacterial growth. Patients completed a satisfaction survey at the end of treatment, and cost of treatment was calculated.


Healing time ranged from 3 to 14 days (mean, 8.1 days). Wound cultures revealed normal bacterial growth on days 1 and 7 for all patients. Patients rated ALH gel favorably, with the most common complaint of stickiness in 5 patients. One patient experienced transient burning on application that did not interrupt treatment. Average hospital-based cost of treatment was $26.15 per patient.


Healing time was congruent with or better than what would have been expected with standard treatment. Furthermore, despite no antibiotic treatment, wound culture results yielded no abnormal bacterial growth. Finally, patients overall reported satisfaction with treatment. The findings of this study suggest that ALH is a clinically and economically valuable treatment for partial-thickness facial burns.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center