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Int J Infect Dis. 2016 Sep;50:10-7. doi: 10.1016/j.ijid.2016.07.006. Epub 2016 Jul 12.

Morganella morganii, a non-negligent opportunistic pathogen.

Author information

1
Department of Microbiology, College of Basic Medical Sciences, Third Military Medical University, Chongqing 400038, China.
2
Department of Microbiology, College of Basic Medical Sciences, Third Military Medical University, Chongqing 400038, China. Electronic address: raoxiancai@126.com.

Abstract

Morganella morganii belongs to the tribe Proteeae of the Enterobacteriaceae family. This species is considered as an unusual opportunistic pathogen that mainly causes post-operative wound and urinary tract infections. However, certain clinical M. morganii isolates present resistance to multiple antibiotics by carrying various resistant genes (such as blaNDM-1, and qnrD1), thereby posing a serious challenge for clinical infection control. Moreover, virulence evolution makes M. morganii an important pathogen. Accumulated data have demonstrated that M. morganii can cause various infections, such as sepsis, abscess, purple urine bag syndrome, chorioamnionitis, and cellulitis. This bacterium often results in a high mortality rate in patients with some infections. M. morganii is considered as a non-negligent opportunistic pathogen because of the increased levels of resistance and virulence. In this review, we summarized the epidemiology of M. morganii, particularly on its resistance profile and resistant genes, as well as the disease spectrum and risk factors for its infection.

KEYWORDS:

Morganella morganii; disease spectrum; epidemiology; resistant genes; risk factors.

PMID:
27421818
DOI:
10.1016/j.ijid.2016.07.006
[Indexed for MEDLINE]
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