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Forensic Sci Int Genet. 2016 Sep;24:e14-e16. doi: 10.1016/j.fsigen.2016.06.017. Epub 2016 Jun 22.

Genetic polymorphism of 22 autosomal STR markers in a Han population of Southern China.

Author information

1
Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Suzhou Microread Genetics Co., Ltd., China, Room 312, No.15 Building, Biomedical Engineering Park, No.8 Jinfeng Road, SND, Suzhou 215163, Jiangsu, PR China; Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China. Electronic address: liuql@mail.sysu.edu.cn.
2
Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Suzhou Microread Genetics Co., Ltd., China, Room 312, No.15 Building, Biomedical Engineering Park, No.8 Jinfeng Road, SND, Suzhou 215163, Jiangsu, PR China; Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China. Electronic address: lanczx@163.com.
3
Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Suzhou Microread Genetics Co., Ltd., China, Room 312, No.15 Building, Biomedical Engineering Park, No.8 Jinfeng Road, SND, Suzhou 215163, Jiangsu, PR China; Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China. Electronic address: mr_ccg@126.com.
4
Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Suzhou Microread Genetics Co., Ltd., China, Room 312, No.15 Building, Biomedical Engineering Park, No.8 Jinfeng Road, SND, Suzhou 215163, Jiangsu, PR China; Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China. Electronic address: lvdejian@mail.sysu.edu.cn.

Abstract

Population genetic data and forensic statistics of 22 autosomal short tandem repeat (STR) loci (D1S1656, D2S1338, D3S3045, D4S2366, D5S2500, D6S477, D7S3048, D8S1132, D9S925, D10S1435, D11S2368, D12S391, D13S325, D14S608, D15S659, D16S539, D17S1290, D18S535, D19S253, D20S470, D21S1270 and GATA198B05) were determined for a sample of 515 unrelated individuals from Han population in Southern China. The expected heterozygosity and the discrimination power varied from 0.7358 to 0.8733 and 0.8915 to 0.9702, respectively. The probability of excluding an unrelated man as the true father (assuming no background relatedness in the population) for trios and for duos ranged from 0.5126 to 0.7415 and 0.3331 to 0.5864, respectively. The studied STRs appear to provide a significant improvement in the statistical power of kinship analysis.

KEYWORDS:

Chinese Han population; Kinship analysis; Linkage disequilibrium; Population data; Short tandem repeats (STR)

PMID:
27421761
DOI:
10.1016/j.fsigen.2016.06.017
[Indexed for MEDLINE]

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