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Br Med Bull. 2016 Sep;119(1):63-74. doi: 10.1093/bmb/ldw027. Epub 2016 Jul 14.

Novel biomarkers predicting cardiac function after acute myocardial infarction.

Author information

1
Department of Cardiology and Angiology, University Clinic of Internal Medicine III, Medical University of Innsbruck, Anichstraße 35, A-6020 Innsbruck, Austria.
2
Department of Radiology, Medical University of Innsbruck, Anichstraße 35, A-6020 Innsbruck, Austria.
3
Department of Cardiology and Angiology, University Clinic of Internal Medicine III, Medical University of Innsbruck, Anichstraße 35, A-6020 Innsbruck, Austria Bernhard.Metzler@tirol-kliniken.at.

Abstract

BACKGROUND:

Measurement of biomarkers provides a cost-effective and widely available method to estimate cardiac dysfunction and clinical outcome of patients with acute myocardial infarction (AMI).

SOURCES OF DATA:

PubMed entries with terms 'myocardial infarction' and the respective biomarker.

AREAS OF AGREEMENT:

Cardiac troponins and natriuretic peptides are closely related to left ventricular dysfunction and the occurrence of adverse clinical events following AMI.

AREAS OF CONTENTION:

The incremental value of novel biomarkers is controversial.

FUTURE DIRECTIONS:

The combination of traditional and novel biomarkers might further improve risk stratification of patients with AMI.

SEARCH STRATEGY:

We searched all entries on the PubMed database with the MeSH terms 'myocardial infarction' and 'cardiac troponins', 'natriuretic peptides', 'copeptin', galectin-3', 'corin', 'fetuin-A', 'adiponectin' and 'microRNA'.

KEYWORDS:

acute myocardial infarction; biomarkers; cardiac function; prognosis

PMID:
27418651
DOI:
10.1093/bmb/ldw027
[Indexed for MEDLINE]

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