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Clin Infect Dis. 2016 Nov 1;63(9):1198-1201. Epub 2016 Jul 14.

Zika Virus Infection Associated With Severe Thrombocytopenia.

Author information

1
Dengue Branch.
2
Puerto Rico Department of Health, San Juan.
3
Division of Vector-Borne Diseases University of Colorado, Denver.
4
Epidemic Intelligence Service.
5
San Juan City Hospital.
6
Hospital HIMA San Pablo, Bayamón, Puerto Rico.
7
Arboviral Diseases Branch, Centers for Disease Control and Prevention.

Abstract

We report two patients that developed severe thrombocytopenia after Zika virus (ZIKV) infection. The first patient had 1000 platelets/μL and died after multiple hemorrhages. The second patient had 2000 platelets/μL, had melena and ecchymoses, and recovered after receiving intravenous immunoglobulin. ZIKV may be associated with immune-mediated severe thrombocytopenia.

KEYWORDS:

Puerto Rico; Zika virus; fatal; thrombocytopenia

PMID:
27418575
PMCID:
PMC5176332
DOI:
10.1093/cid/ciw476
[Indexed for MEDLINE]
Free PMC Article

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