[Astrocytoma and epilepsy. Clinical case]

Cir Cir. 2017 Sep-Oct;85(5):419-423. doi: 10.1016/j.circir.2016.05.009. Epub 2016 Jul 11.
[Article in Spanish]

Abstract

Background: Pilocytic astrocytoma is a rare tumour, usually occurring in paediatric ages, and mainly located in the posterior fossa. It can cause hydrocephalus and intracranial hypertension and, less frequently, seizures, or a focal neurological deficit. The main imaging study by magnetic resonance imaging, which shows a tumour with solid and cystic components without peri-lesional swelling. The election treatment is surgical, and the patient is considered cured if a total resection is accomplished.

Clinical case: The case is presented of 22-year-old female patient with a supratentorial pilocytic astrocytoma and epilepsy. Histopathology reported a low grade glial proliferation, with an extensive fibrillar matrix, small cells without atypia, extensive calcifications and piloid areas consisting of bipolar fusiform cells, and some Rosenthal fibres. There were also spongiotic areas consisting of multipolar cells and associated microcysts. The final report was a pilocytic astrocytoma.

Conclusions: Pilocytic astrocytoma is more frequent in paediatric patients and in the posterior fossa. The case presented is of a young female adult with supratentorial location, making it a special case. The surgery achieved a total resection. The long-term prognosis is good, but it is necessary to perform a follow-up, particularly in adult patients because of a higher risk of recurrence.

Keywords: Adulto joven; Astrocitoma pilocítico; Pilocytic astrocytoma; Supratentorial tumours; Tumor supratentorial; Young adult.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anticonvulsants / therapeutic use
  • Astrocytoma / complications*
  • Astrocytoma / diagnostic imaging
  • Astrocytoma / pathology
  • Astrocytoma / surgery
  • Cholecystitis, Acute / complications
  • Craniotomy / methods*
  • Female
  • Humans
  • Levetiracetam
  • Magnetic Resonance Imaging
  • Neuroimaging
  • Piracetam / analogs & derivatives
  • Piracetam / therapeutic use
  • Remission Induction
  • Seizures / drug therapy
  • Seizures / etiology*
  • Supratentorial Neoplasms / complications*
  • Supratentorial Neoplasms / diagnostic imaging
  • Supratentorial Neoplasms / pathology
  • Supratentorial Neoplasms / surgery
  • Young Adult

Substances

  • Anticonvulsants
  • Levetiracetam
  • Piracetam