Format

Send to

Choose Destination
Gastroenterol Hepatol. 2016 Dec;39(10):656-662. doi: 10.1016/j.gastrohep.2016.05.002. Epub 2016 Jul 11.

Hepatitis C seroprevalence in an at-risk population in the southwest Madrid region of Spain.

[Article in English, Spanish]

Author information

1
Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, España.
2
Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, España; Unidad de Digestivo, Departamento de Medicina, Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Móstoles, Madrid, España.
3
Centro de Salud Ramón y Cajal, Dirección Asistencial Oeste, Madrid, España.
4
Centro de Salud Gregorio Marañón, Dirección Asistencial Oeste, Madrid, España.
5
Centro de Salud Miguel Servet, Dirección Asistencial Oeste, Madrid, España.
6
Centro de Salud Los Castillos, Dirección Asistencial Oeste, Madrid, España.
7
Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, España; Servicio de Medicina Preventiva, Departamento de Medicina Preventiva y Salud Pública, Facultad Ciencias de la Salud, Universidad Rey Juan Carlos, Alcorcón, Madrid, España.
8
Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, España. Electronic address: cfernandez@fhalcorcon.es.

Abstract

INTRODUCTION:

The estimated seroprevalence of hepatitis C virus (HCV) in Spain is 1.7%, but is much higher in the at-risk population. The most efficient national screening strategy is unclear.

AIMS:

To estimate the prevalence of HCV among the at-risk population seen in primary care (PC), and to determine their epidemiological profile.

MATERIALS AND METHODS:

Cross-sectional descriptive prevalence study that included adult patients with risk factors for HCV infection seen in PC in the southwest Madrid region between 2010 and 2012.

RESULTS:

A total of 158 patients (men=51.3%), mean age 46 years (SD=16.6), were included. The most common risk factors were hypertransaminasaemia (44.3%) and major surgery (13.3%). Immigration, unsafe sexual practices, and tattoos or body piercing were more prevalent in patients younger than 45 years of age. Fifteen patients (9.5%) were positive for anti-HCV; 9 of these (5.7%) were HCV-ARN positive. Of the positive patients, 4 (44.4%) had significant fibrosis at diagnosis (F3-F4). Male patients had a higher rate of positive anti-HCV results (13.8 vs. 5.3%; P=.072), as did patients older than 45 years of age (12.8 vs. 6.3%; P=.167). Intravenous and intranasal drug use were associated with a higher rate of positive anti-HCV results (50 vs. 8.5%; P=.005 and 66.7 vs. 8.4%; P=.001, respectively).

CONCLUSIONS:

Patients with risk factors for HCV infection have high seroprevalence. Screening programmes must therefore be implemented to detect HCV infection in this population in PC.

KEYWORDS:

Anti-HCV antibodies; Anticuerpos anti-VHC; Cribado; Factores de riesgo; Risk factors; Screening; Seroprevalence; Seroprevalencia

PMID:
27417563
DOI:
10.1016/j.gastrohep.2016.05.002
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Ediciones Doyma, S.L.
Loading ...
Support Center