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Appropriate use of red blood cell transfusion in emergency departments: a study in five emergency departments.

Díaz MQ, Borobia AM, García Erce JA, Maroun-Eid C, Fabra S, Carcas A, Frías J, Muñoz M; USEES-URG Research Group.

Blood Transfus. 2017 May;15(3):199-206. doi: 10.2450/2016.0324-15. Epub 2016 Jul 7.


Public preferences on written informed consent for low-risk pragmatic clinical trials in Spain.

Dal-Ré R, Carcas AJ, Carné X, Wendler D.

Br J Clin Pharmacol. 2017 Sep;83(9):1921-1931. doi: 10.1111/bcp.13305. Epub 2017 Jun 11.


Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor.

Longhurst H, Cicardi M, Craig T, Bork K, Grattan C, Baker J, Li HH, Reshef A, Bonner J, Bernstein JA, Anderson J, Lumry WR, Farkas H, Katelaris CH, Sussman GL, Jacobs J, Riedl M, Manning ME, Hebert J, Keith PK, Kivity S, Neri S, Levy DS, Baeza ML, Nathan R, Schwartz LB, Caballero T, Yang W, Crisan I, Hernandez MD, Hussain I, Tarzi M, Ritchie B, Králíčková P, Guilarte M, Rehman SM, Banerji A, Gower RG, Bensen-Kennedy D, Edelman J, Feuersenger H, Lawo JP, Machnig T, Pawaskar D, Pragst I, Zuraw BL; COMPACT Investigators.

N Engl J Med. 2017 Mar 23;376(12):1131-1140. doi: 10.1056/NEJMoa1613627.


Eosinophilic drug reactions detected by a prospective pharmacovigilance programme in a tertiary hospital.

Ramírez E, Medrano-Casique N, Tong HY, Bellón T, Cabañas R, Fiandor A, González-Ramos J, Herranz P, Trigo E, Muñoz M, Borobia AM, Carcas AJ, Frías J.

Br J Clin Pharmacol. 2017 Feb;83(2):400-415. doi: 10.1111/bcp.13096. Epub 2016 Oct 12.


Hepatotoxicity induced by acute and chronic paracetamol overdose in children: Where do we stand?

Tong HY, Medrano N, Borobia AM, Ruiz JA, Martínez AM, Martín J, Quintana M, García S, Carcas AJ, Ramírez E.

World J Pediatr. 2017 Feb;13(1):76-83. doi: 10.1007/s12519-016-0046-6. Epub 2016 Jul 15.


A fast-track anaemia clinic in the Emergency Department: cost-analysis of intravenous iron administration for treating iron-deficiency anaemia.

Quintana-Díaz M, Muñoz-Romo R, Gómez-Ramírez S, Pavía J, Borobia AM, García-Erce JA, Muñoz M.

Blood Transfus. 2017 Sep;15(5):438-446. doi: 10.2450/2017.0282-16. Epub 2017 Jan 24.


Weight of ABCB1 and POR genes on oral tacrolimus exposure in CYP3A5 nonexpressor pediatric patients with stable kidney transplant.

Almeida-Paulo GN, Dapía García I, Lubomirov R, Borobia AM, Alonso-Sánchez NL, Espinosa L, Carcas-Sansuán AJ.

Pharmacogenomics J. 2018 Jan;18(1):180-186. doi: 10.1038/tpj.2016.93. Epub 2017 Jan 17.


Significant HLA class I type associations with aromatic antiepileptic drug (AED)-induced SJS/TEN are different from those found for the same AED-induced DRESS in the Spanish population.

Ramírez E, Bellón T, Tong HY, Borobia AM, de Abajo FJ, Lerma V, Moreno Hidalgo MA, Castañer JL, Cabañas R, Fiandor A, González-Ramos J, Herranz P, Cachafeiro L, González-Herrada C, González O, Aramburu JA, Laosa O, Hernández R, Carcas AJ, Frías J.

Pharmacol Res. 2017 Jan;115:168-178. doi: 10.1016/j.phrs.2016.11.027. Epub 2016 Nov 22.


Nonchemotherapy drug-induced agranulocytosis in children detected by a prospective pharmacovigilance program.

Medrano-Casique N, Tong HY, Borobia AM, Carcas AJ, Frías J, Ramírez E.

Pediatr Hematol Oncol. 2016 Oct - Nov;33(7-8):441-456. Epub 2016 Dec 6.


Two cases of overlap severe cutaneous adverse reactions to benznidazole treatment for asymptomatic Chagas disease in a nonendemic country.

González-Ramos J, Noguera-Morel L, Tong HY, Ramírez E, Ruiz-Bravo E, Bellón T, Cabañas R, Cachafeiro L, Herranz-Pinto P.

Br J Dermatol. 2016 Sep;175(3):604-7. doi: 10.1111/bjd.14451. Epub 2016 Apr 7.


Limited sampling strategies for once daily tacrolimus exposure monitoring.

Carcas-Sansuán AJ.

Eur J Clin Pharmacol. 2016 Jun;72(6):773-4. doi: 10.1007/s00228-016-2035-z. Epub 2016 Mar 3. No abstract available.


Invasive aspergillosis in a paediatric allogeneic stem cell transplantation recipient owing to a susceptible Aspergillus fumigatus: Treatment failure with high doses of voriconazole and influence of CYP2C19 polymorphisms.

Cendejas-Bueno E, Borobia AM, Gomez-Lopez A, Escosa-García L, Río-García M, Plaza D, García-Rodriguez J, Carcas-Sansuán A.

Int J Antimicrob Agents. 2016 May;47(5):410-1. doi: 10.1016/j.ijantimicag.2016.02.002. Epub 2016 Feb 27. No abstract available.


Outcomes and Costs of Poisoned Patients Admitted to an Adult Emergency Department of a Spanish Tertiary Hospital: Evaluation through a Toxicovigilance Program.

Muñoz R, Borobia AM, Quintana M, Martínez A, Ramírez E, Muñoz M, Frías J, Carcas AJ.

PLoS One. 2016 Apr 21;11(4):e0152876. doi: 10.1371/journal.pone.0152876. eCollection 2016.


The HLA-B*15:02 allele in a Spanish Romani patient with carbamazepine-induced Stevens-Johnson syndrome.

Bellón T, Ramírez E, Borobia AM, Lerma V, Moreno-Hidalgo MA, Laosa O, Aramburu JA, González-Herrada C, de Abajo FJ.

Pharmacogenomics. 2016 Apr;17(6):541-5. doi: 10.2217/pgs.16.10. Epub 2016 Mar 29.


A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population.

Tong HY, Dávila-Fajardo CL, Borobia AM, Martínez-González LJ, Lubomirov R, Perea León LM, Blanco Bañares MJ, Díaz-Villamarín X, Fernández-Capitán C, Cabeza Barrera J, Carcas AJ; PGX-ACE Investigators Group.

PLoS One. 2016 Mar 15;11(3):e0150456. doi: 10.1371/journal.pone.0150456. eCollection 2016.


Non-Chemotherapy-Induced Agranulocytosis Detected by a Prospective Pharmacovigilance Program in a Tertiary Hospital.

Medrano-Casique N, Tong HY, Borobia AM, Carcas AJ, Frías J, Ramírez E.

Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):399-408. doi: 10.1111/bcpt.12418. Epub 2015 Jun 11.


[Electronic medical record in clinical trials of effectiveness of drugs integrated in clinical practice].

Carcas AJ, Abad Santos F, Sánchez Perruca L, Dal-Ré R.

Med Clin (Barc). 2015 Nov 20;145(10):452-7. doi: 10.1016/j.medcli.2015.01.028. Epub 2015 Apr 23. Spanish. No abstract available.


Acute respiratory distress syndrome after convalescent plasma use: treatment of a patient with Ebola virus disease contracted in Madrid, Spain.

Mora-Rillo M, Arsuaga M, Ramírez-Olivencia G, de la Calle F, Borobia AM, Sánchez-Seco P, Lago M, Figueira JC, Fernández-Puntero B, Viejo A, Negredo A, Nuñez C, Flores E, Carcas AJ, Jiménez-Yuste V, Lasala F, García-de-Lorenzo A, Arnalich F, Arribas JR; La Paz-Carlos III University Hospital Isolation Unit.

Lancet Respir Med. 2015 Jul;3(7):554-62. doi: 10.1016/S2213-2600(15)00180-0. Epub 2015 May 31. Review.


Hepatotoxicity induced by acute and chronic paracetamol overdose in adults. Where do we stand?

Tong HY, Medrano N, Borobia AM, Martínez AM, Martín J, Ruiz JA, García S, Quintana M, Carcas AJ, Frías J, Ramírez E.

Regul Toxicol Pharmacol. 2015 Jul;72(2):370-8. doi: 10.1016/j.yrtph.2015.05.011. Epub 2015 May 16.


Pharmacogenetics of quetiapine in healthy volunteers: association with pharmacokinetics, pharmacodynamics, and adverse effects.

Cabaleiro T, López-Rodríguez R, Román M, Ochoa D, Novalbos J, Borobia A, Carcas A, Abad-Santos F.

Int Clin Psychopharmacol. 2015 Mar;30(2):82-8. doi: 10.1097/YIC.0000000000000047.


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