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Nat Med. 2016 Aug;22(8):839-50. doi: 10.1038/nm.4108. Epub 2016 Jul 11.

International AIDS Society global scientific strategy: towards an HIV cure 2016.

Author information

1
Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
2
The Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
3
Department of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, Australia.
4
International and Scientific Relations Office, ANRS, Paris, France.
5
US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
6
Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
7
Molecular Virology Lab, Institute of Human Genetics, CNRS UPR 1142, Université de Montpellier, Montpellier, France.
8
Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
9
CRCHUM and Department of Microbiology, Infectiology, and Immunology, Université de Montréal, Faculty of Medicine, Montréal, Quebec, Canada.
10
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
11
AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, Maryland, USA.
12
World Health Organization Regional Office for the Western Pacific, Manila, Philippines.
13
Brigham &Women's Hospital, Boston, Massachusetts, USA.
14
University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
15
Division of Infectious Diseases, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
16
Johns Hopkins University School of Medicine &Bloomberg School of Public Health, Baltimore, Maryland, USA.
17
University of North Carolina-Project China, Guangzhou, China.
18
Institut Pasteur, Paris, France.
19
Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, USA.
20
Sorbonne Universités, UPMC Univ Paris 06, CIMI-Paris, France.
21
Inserm U1135, CIMI-Paris, Paris, France.
22
AP-HP, Hôpital Pitié-Salpêtrière, Département d'Immunologie, Paris, France.
23
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
24
Clinic for Immunology and Rhematology, Hannover Medical School, Hanover, Germany.
25
Centre d'Investigation Clinique en biothérapie, Hôpital Necker-Enfants Malades, Paris, France.
26
AIDS Institute, The University of Hong Kong, Pok Fu Lam, Hong Kong.
27
Institut de Recherches Cliniques de Montréal, Université de Montréal, Montréal, Quebec, Canada.
28
European AIDS Treatment Group, Italy.
29
Programme PAC-CI, Centre Hospitalier Universitaire de Treichville, Abidjan, Côte d'Ivoire.
30
Harvard T. H. Chan School of Public Health, Department of Global Health and Population, Boston, Massachusetts, USA.
31
Department of Medicine, Imperial College London, London, United Kingdom.
32
The B-Change Group, Manila, Philippines.
33
National Institute of Mental Health, NIH, Bethesda, Maryland, USA.
34
Treatment Action Group, New York, New York, USA.
35
Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
36
Centre for Medical Ethics and Law, Department of Medicine, Stellenbosch University, Western Cape, South Africa.
37
Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.
38
Department of Medical Microbiology, Virology, University Medical Center Utrecht, Utrecht, Netherlands.
39
Joint Clinical Research Centre, Kampala, Uganda.
40
Gladstone Institutes, University of California, San Francisco, San Francisco, California, USA.
41
Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, Australia.
42
Virginia San Diego Healthcare System and University of California, San Diego, San Diego, California, USA.
43
Independent HIV Education and Advocacy Consultant, San Francisco, California, USA.
44
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
45
Yerkes National Primate Research Centre, Emory University, Atlanta, Georgia, USA.
46
Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
47
INSERM UMR_S912, Marseille, France.
48
CARE Collaboratory Community Advisory Board, Palm Springs, California, USA.
49
Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
50
Department of Immunology and Microbial Sciences, The Scripps Research Institute, Jupiter, Florida, USA.
51
ViiV Healthcare, London, United Kingdom.
52
Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
53
Department of Health Services, Policy &Practice, Brown University School of Public Health, Providence, Rhode Island, USA.
54
David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

Abstract

Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a global population of more than 35 million people living with HIV, there is intense interest in developing a cure for HIV infection. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. This Perspective summarizes the group's strategy.

PMID:
27400264
PMCID:
PMC5322797
DOI:
10.1038/nm.4108
[Indexed for MEDLINE]
Free PMC Article

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