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Eur Respir J. 2016 Sep;48(3):852-60. doi: 10.1183/13993003.02049-2015. Epub 2016 Jul 7.

Defining a standard set of patient-centred outcomes for lung cancer.

Author information

1
International Consortium for Health Outcomes Measurement, Cambridge, MA, USA Harvard Radiation Oncology Program, Boston, MA, USA Boston Medical Center, Dept of Radiation Oncology, Boston, MA, USA Both authors contributed equally.
2
International Consortium for Health Outcomes Measurement, Cambridge, MA, USA Dutch Institute for Clinical Auditing, Leiden, The Netherlands Both authors contributed equally.
3
International Consortium for Health Outcomes Measurement, Cambridge, MA, USA.
4
Dept of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, MA, USA.
5
Patient representative, Manchester, UK.
6
Dept of Medical Oncology, Clínicas Oncológicas Integradas, Rio de Janeiro, Brazil.
7
Dept of Respiratory Medicine, Nottingham University Hospitals, Nottingham, UK.
8
Dept of Thoracic Oncology, Edinburgh Cancer Research Centre, Edinburgh, UK.
9
Dept of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
10
Dept of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
11
Roy Castle Lung Cancer Foundation, Liverpool, UK.
12
Patient representative, Glasgow, UK.
13
Dept of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA.
14
Dept of Thoracic Surgery, University of Virginia Health System, Charlottesville, VA, USA.
15
Dept of Thoracic and Cardiovascular Surgery, MD Anderson Cancer Center, Houston, TX, USA.
16
Dept of Pulmonology, St Antonius Hospital, Nieuwegein, The Netherlands.
17
Dept of Radiation Oncology, VU University Medical Centre, Amsterdam, The Netherlands.
18
Dept of Allergy Immunology and Respiratory Medicine, Alfred Hospital, Monash University, Melbourne, Australia.
19
Dept of Thoracic Oncology, Antwerp University Hospital, Edegem, Belgium.
20
Dept of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands Scientific Bureau, Dutch Institute for Clinical Auditing, Leiden, The Netherlands.
21
Dept of Respiratory Medicine, University Hospitals of Leicester, Leicester, UK National Cancer Registration and Analysis Service (NCRAS), Public Health England, London, UK mick.peake@uhl-tr.nhs.uk.

Abstract

In lung cancer, outcome measurement has been mostly limited to survival. Proper assessment of the value of lung cancer treatments, and the performance of institutions delivering care, requires more comprehensive measurement of standardised outcomes.The International Consortium for Health Outcomes Measurement convened an international, multidisciplinary working group of patient representatives, medical oncologists, surgeons, radiation oncologists, pulmonologists, palliative care specialists, registry experts and specialist nurses to review existing data and practices. Using a modified Delphi method, the group developed a consensus recommendation ("the set") on the outcomes most essential to track for patients with lung cancer, along with baseline demographic, clinical and tumour characteristics (case-mix variables) for risk adjustment.The set applies to patients diagnosed with nonsmall cell lung cancer and small cell lung cancer. Our working group recommends the collection of the following outcomes: survival, complications during or within 6 months of treatment and patient-reported domains of health-related quality of life including pain, fatigue, cough and dyspnoea. Case-mix variables were defined to improve interpretation of comparisons.We defined an international consensus recommendation of the most important outcomes for lung cancer patients, along with relevant case-mix variables, and are working to support adoption and reporting of these measures globally.

PMID:
27390281
PMCID:
PMC5007221
DOI:
10.1183/13993003.02049-2015
[Indexed for MEDLINE]
Free PMC Article

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