A Novel Rearranged Taxoid from Needles of the Japanese Yew, Taxus cuspidata Sieb. et Zucc

R Murakami; Q W Shi; T Horiguchi; T Oritani

doi:10.1271/bbb.63.1660

A Novel Rearranged Taxoid from Needles of the Japanese Yew, Taxus cuspidata Sieb. et Zucc

Biosci Biotechnol Biochem. 1999;63(9):1660-3. doi: 10.1271/bbb.63.1660.

Authors

R Murakami¹, Q W Shi¹, T Horiguchi¹, T Oritani¹

Affiliation

¹ a Laboratory of Applied Bioorganic Chemistry, Division of Life Science, Graduate School of Agricultural Science, Tohoku University.

PMID: 27389652
DOI: 10.1271/bbb.63.1660

Abstract

Eleven taxoids were isolated from needles of the Japanese yew, Taxus cuspidata Sieb. et Zucc., one of them being a new compound whose structure was established as 5α-cinnamoyl-9α,10β,13α-triacetoxy-11(15→1)abeotaxa-4(20),11-dien-15-ol (7-deactoxytaxuspine J) on the basis of a spectroscopic analysis. Its relative stereochemistry is proposed from the results of a NOESY experiment.

Keywords: Taxaceae; Taxus; Taxus cuspidata; needle; taxane diterpenoid.