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Harv Rev Psychiatry. 2016 Jul-Aug;24(4):271-93. doi: 10.1097/HRP.0000000000000106.

Posttraumatic Stress Disorder, Overweight, and Obesity: A Systematic Review and Meta-analysis.

Author information

1
From the Department of Psychiatry, Stellenbosch University, Cape Town, South Africa.

Abstract

Previous reports have suggested a high prevalence of overweight and obesity among individuals with posttraumatic stress disorder (PTSD). Few studies, however, systematically analyze the relationship between PTSD and body mass index (BMI). We conducted a systematic review and meta-analysis aimed at estimating the association between PTSD and BMI. Fifty-four articles were reviewed, 30 of which (with 191,948 individuals with PTSD and 418,690 trauma-exposed individuals or healthy controls) were eligible for inclusion in the meta-analysis. The pooled standard mean difference, based on a random-effects model, was 0.41 (95% confidence interval, 0.28-0.54; z = 6.26; p < .001). Statistical heterogeneity between the included studies was high (p < .001; I = 99%). Despite limitations, the findings of this systematic review and meta-analysis suggest an association between PTSD and BMI. Furthermore, longitudinal studies tentatively indicate that PTSD may lead to an increase in BMI and, as such, to the development of overweight/obesity, particularly in women. Further prospective studies and research elaborating the nature and etiology of the association are required.

PMID:
27384397
DOI:
10.1097/HRP.0000000000000106
[Indexed for MEDLINE]

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