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Hautarzt. 2016 Nov;67(11):902-906.

[Disseminated necrobiotic xanthogranuloma].

[Article in German]

Author information

1
Klinik für Dermatologie und Allergologie, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr. 41, 01067, Dresden, Deutschland.
2
Institut für Pathologie "Georg Schmorl", Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Dresden, Deutschland.
3
Klinik für Dermatologie und Allergologie, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr. 41, 01067, Dresden, Deutschland. wollina-uw@khdf.de.

Abstract

Necrobiotic xanthogranuloma is a rare non-Langerhans-cell histiocytosis. A 62-year-old woman presented with yellowish erythematous plaques, nodules, and papules in the periorbital region and the extremities. She had a nodular tumor grown on the left upper lid that clinically resembled a keratoacanthoma. Histologically it was a xanthogranulomatous lesion. She suffered from monoclonal gammopathy of unknown significance of κ‑type. Treatment was realized with a combination of systemic dapsone/prednisolone and topical corticosteroids.

KEYWORDS:

Corticosteroids; Dapsone; Dermatology; Monoclonal gammopathy of undetermined significance; Non-Langerhans-cell histiocytosis

PMID:
27380383
DOI:
10.1007/s00105-016-3839-6
[Indexed for MEDLINE]

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