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Bioinformatics. 2016 Nov 1;32(21):3321-3323. Epub 2016 Jul 4.

Icarus: visualizer for de novo assembly evaluation.

Author information

1
Center for Algorithmic Biotechnology, Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia, 199034.
2
Department of Mathematics and Information Technology, St. Petersburg Academic University, Russian Academy of Sciences, St. Petersburg, Russia, 194021.

Abstract

: Data visualization plays an increasingly important role in NGS data analysis. With advances in both sequencing and computational technologies, it has become a new bottleneck in genomics studies. Indeed, evaluation of de novo genome assemblies is one of the areas that can benefit from the visualization. However, even though multiple quality assessment methods are now available, existing visualization tools are hardly suitable for this purpose. Here, we present Icarus-a novel genome visualizer for accurate assessment and analysis of genomic draft assemblies, which is based on the tool QUAST. Icarus can be used in studies where a related reference genome is available, as well as for non-model organisms. The tool is available online and as a standalone application.

AVAILABILITY AND IMPLEMENTATION:

http://cab.spbu.ru/software/icarus CONTACT: aleksey.gurevich@spbu.ruSupplementary information: Supplementary data are available at Bioinformatics online.

PMID:
27378299
DOI:
10.1093/bioinformatics/btw379
[Indexed for MEDLINE]

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