Send to

Choose Destination
See comment in PubMed Commons below
Genomics. 1989 Feb;4(2):218-20.

Chromosomal assignment of the alcohol dehydrogenase cluster locus to human chromosome 4q21-23 by in situ hybridization.

Author information

  • 1Department of Biochemical Genetics, Beckman Research Institute of the City of Hope, Duarte, California 91010.


Human class I alcohol dehydrogenase (alcohol:NAD+ oxidoreductase, EC; ADH) is the major enzyme involved in ethanol oxidation. Three highly homologous genes govern the synthesis of three types of subunits which form several ADH isozymes. The locus for class I ADH loci was previously assigned to q21-25 of chromosome 4 by somatic cell hybridization techniques. Analysis of grain positions by in situ hybridization of chromosomes indicated that the ADH cluster locus is on 4q21-23, probably 4q22.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center