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Toxins (Basel). 2016 Jun 30;8(7). pii: E199. doi: 10.3390/toxins8070199.

Therapeutic Effectiveness of Anticancer Phytochemicals on Cancer Stem Cells.

Author information

1
School of Food Science and Biotechnology (BK21 Plus), Kyungpook National University, Daegu 41566, Korea. j.oh@knu.ac.kr.
2
Center of Cancer Systems Biology, Tufts University School of Medicine, Boston, MA 02135, USA. hlatky@cancer-systems-biology.org.
3
Department of Food Science and Technology, Chonbuk National University, Jeonju 54896, Korea. ysjeong@jbnu.ac.kr.
4
Department of Integrative Physiology and Pathobiology, Tufts University School of Medicine, Boston, MA 02111, USA. dohoon.kim@tufts.edu.

Abstract

Understanding how to target cancer stem cells (CSCs) may provide helpful insights for the development of therapeutic or preventive strategies against cancers. Dietary phytochemicals with anticancer properties are promising candidates and have selective impact on CSCs. This review summarizes the influence of phytochemicals on heterogeneous cancer cell populations as well as on specific targeting of CSCs.

KEYWORDS:

anticancer; cancer; cancer stem cells; phytochemicals; polyphenols

PMID:
27376325
PMCID:
PMC4963832
DOI:
10.3390/toxins8070199
[Indexed for MEDLINE]
Free PMC Article

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