Format

Send to

Choose Destination
Clin Gastroenterol Hepatol. 2017 Jan;15(1):17-24. doi: 10.1016/j.cgh.2016.06.017. Epub 2016 Jun 29.

Gastrointestinal Manifestations of Autosomal-Dominant Polycystic Kidney Disease.

Author information

1
Center for Liver Diseases, The University of Chicago Medicine, Chicago, Illinois. Electronic address: aemikolaj@gmail.com.
2
Center for Liver Diseases, The University of Chicago Medicine, Chicago, Illinois.
3
Section of Nephrology, The University of Chicago Medicine, Chicago, Illinois.

Abstract

Autosomal-dominant polycystic kidney disease (ADPKD) is the most commonly inherited kidney disease, and the fourth most common cause of end-stage renal disease. ADPKD is a systemic disorder, associated with numerous extrarenal manifestations, including polycystic liver disease, the most common gastrointestinal manifestation, and diverticular disease, inguinal, and ventral hernias, pancreatic cysts, and large bile duct abnormalities. All of these gastrointestinal manifestations play a significant role in disease burden in ADPKD, particularly in the later decades of life. Thus, as ADPKD becomes more recognized, it is important for gastroenterologists to be knowledgeable of this monogenic disorder's effects on the digestive system.

KEYWORDS:

ADPKD; Cysts; Diverticulosis; Hernia

PMID:
27374006
DOI:
10.1016/j.cgh.2016.06.017
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center