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Psychol Health Med. 2017 Jan;22(1):28-36. Epub 2016 Jul 1.

The correlations of socioeconomic status, disease activity, quality of life, and depression/anxiety in Chinese patients with rheumatoid arthritis.

Zhang L1,2, Xia Y2, Zhang Q1,2, Fu T1,2, Yin R1,2, Guo G2, Li L1, Gu Z2.

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a School of Nursing , Nantong University , Nantong , China.
b Department of Rheumatology , Affiliated Hospital of Nantong University , Nantong , China.


This study aimed (i) to investigate the relationships among socioeconomic status, disease activity, quality of life, and the psychological status in Chinese rheumatoid arthritis (RA) patients; (ii) to explore the possible risk factors of anxiety and depression. A total of 160 RA patients underwent standardized laboratory examinations and completed several questionnaires. Independent samples t-tests, χ2 analyses, and logistic regression modeling were used to analyze the data. We found 30.6% RA patients were anxiety, and 27.5% had depression, which were significantly higher than the control group (7.8 and 11.7%, respectively). And there were significant correlations among education, pain, disease activity, medication adherence, functional capacity, quality of life, and anxiety/depression. Meanwhile, logistic regression analysis revealed that poor quality of life and low education level were significantly associated with anxiety/depression in RA patients. In conclusion, there were significant relationships among education, quality of life, and anxiety/depression in Chinese RA patients.


Rheumatoid arthritis; anxiety; depression; quality of life

[Indexed for MEDLINE]

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