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World J Hepatol. 2016 Jun 28;8(18):749-56. doi: 10.4254/wjh.v8.i18.749.

Quality of life after liver transplantation: State of the art.

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Louis Onghena, Wouter Develtere, Anja Geerts, Hans Van Vlierberghe, Xavier Verhelst, Department of Hepatology and Gastroenterology, Ghent University Hospital, 9000 Ghent, East Flanders, Belgium.


Quality of life (QoL) after deceased donor liver transplantation is increasingly recognized as a major outcome parameter. We reviewed recent publications in this rapidly evolving field in order to summarize recent achievements in the field and to define opportunities and perspectives for research and improvement of patient care. QoL does improve after liver transplantation according to a typical pattern. During the first year, there is a significant improvement in QoL. After one year, the improvement does stabilise and tends to decline slightly. In addition to the physical condition, different psychological parameters (such as depression, anxiety, sexual function) and sociodemographic elements (professional state, sex, marital state) seem to impact QoL. Opportunities for further research are the use of dedicated questionnaires and identification of influencing factors for QoL.


Demographic factors; Epidemiologic factors; Liver transplantation; Mental health; Quality of life; Sociological factors

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