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Clin Plast Surg. 2016 Jul;43(3):473-88. doi: 10.1016/j.cps.2016.03.017.

Fat, Stem Cells, and Platelet-Rich Plasma.

Author information

1
Department of Plastic Surgery, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA.
2
Department of Plastic Surgery, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA; Department of Plastic Surgery, New York University Langone Medical Center, 44 Hudson Street, New York, NY 10013, USA; Private Practice, Tribeca Plastic Surgery, New York, NY.
3
Department of Plastic Surgery, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA; Department of Bioengineering, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15261, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA. Electronic address: rubipj@UPMC.EDU.

Abstract

The ideal filler for aesthetic surgery is inexpensive and easy to obtain, natural in appearance and texture, immunologically compatible, and long lasting without risk of infection. By most metrics, autologous fat grafts meet these criteria perfectly. Although facial fat grafting is now a commonly accepted surgical procedure, there has been a wave of activity applying stem cells and platelet-rich plasma (PRP) therapies to aesthetic practice. This article addresses technical considerations in the use of autologous fat transfer for facial rejuvenation, and also explores the current evidence for these stem cell and PRP therapies in aesthetic practice.

KEYWORDS:

Adipose-derived stem cells; Autologous fat; Coleman technique; Facial augmentation; Facial rejuvenation; Fat; Fat grafting; Lipoaspirate; PRP; Platelet-rich plasma; Regenerative medicine; Stem cells; Stromal vascular fraction; Structural fat grafting

PMID:
27363761
DOI:
10.1016/j.cps.2016.03.017
[Indexed for MEDLINE]

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