Format

Send to

Choose Destination
Pediatr Res. 2016 Nov;80(5):656-662. doi: 10.1038/pr.2016.134. Epub 2016 Jun 30.

Prenatal DHA supplementation and infant attention.

Author information

1
Department of Psychology, Schiefelbusch Institute for Life Span Studies, University of Kansas, Lawrence, Kansas.
2
Department of Neurology, University of Kansas Medical Center, Lawrence, Kansas.
3
Department of Biostatistics, University of Kansas Medical Center, Lawrence, Kansas.
4
Department of Dietetics and Nutrition, University of Kansas Medical Center, Lawrence, Kansas.
5
Department of Occupational Therapy, Washington University of St. Louis, St. Louis, Missouri.
6
Department of Psychology, Indiana State University, Terre Haute, Indiana.

Abstract

BACKGROUND:

Results of randomized trials on the effects of prenatal docosahexaenoic acid (DHA) on infant cognition are mixed, but most trials have used global standardized outcomes, which may not be sensitive to effects of DHA on specific cognitive domains.

METHODS:

Women were randomized to 600 mg/d DHA or a placebo for the last two trimesters of pregnancy. Infants of these mothers were then followed on tests of visual habituation at 4, 6, and 9 mo of age.

RESULTS:

DHA supplementation did not affect look duration or habituation parameters but infants of supplemented mothers maintained high levels of sustained attention (SA) across the first year; SA declined for the placebo group. The supplemented group also showed significantly reduced attrition on habituation tasks, especially at 6 and 9 mo.

CONCLUSION:

The findings support with the suggestion that prenatal DHA may positively affect infants' attention and regulation of state.

TRIAL REGISTRATION:

ClinicalTrials.gov NCT00266825.

PMID:
27362506
PMCID:
PMC5164926
DOI:
10.1038/pr.2016.134
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center