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J Optom. 2017 Apr - Jun;10(2):135-138. doi: 10.1016/j.optom.2016.04.001. Epub 2016 Jun 24.

Multichannel perimetric alterations in systemic lupus erythematosus treated with hydroxychloroquine.

Author information

1
Grupo de Óptica y Percepción Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain; Department of Ophthalmology (OFTALMAR), Medimar International Hospital, Alicante, Spain; Foundation for the Visual Quality (Fundación para la Calidad Visual, FUNCAVIS), Alicante, Spain.
2
Grupo de Óptica y Percepción Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain.
3
Grupo de Óptica y Percepción Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain. Electronic address: dolores.fez@ua.es.

Abstract

Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease of unknown etiology with many clinical manifestations. We report the first case of SLE in which visual alterations were evaluated with multichannel perimetry. Some achromatic and color vision alterations may be present in SLE, especially when treated with hydroxychloroquine. The sensitivity losses detected in the chromatic channels in the central zone of the visual field were consistent with the results of the FM 100 Hue color test. Likewise, the multichannel perimetry detected sensitivity losses in the parafoveal area for both chromatic channels, especially for the blue-yellow.

KEYWORDS:

Contrast sensitivity; Hydroxychloroquine maculopathy; Lupus disease; Lupus eritematoso; Maculopatía por hidroxicloroquina; Multichannel perimetry; Perimetría multicanal; Sensibilidad al contraste; Visual pathways; Vías visuales

PMID:
27349992
PMCID:
PMC5383461
DOI:
10.1016/j.optom.2016.04.001
[Indexed for MEDLINE]
Free PMC Article

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