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Cogn Neuropsychol. 2016 Jul-Sep;33(5-6):329-42. doi: 10.1080/02643294.2016.1179179. Epub 2016 Jun 24.

Wh- questions and passive sentences in non-fluent variant PPA and semantic variant PPA: Longitudinal findings of an anagram production task.

Cupit J1,2, Graham NL1,2, Leonard C1,3, Tang-Wai D4,5, Black SE6,7,8,9,10,5,11, Rochon E1,2.

Author information

1
a Department of Speech-Language Pathology , Faculty of Medicine, University of Toronto , Toronto , ON , Canada.
2
b Toronto Rehabilitation Institute-University Health Network (TRI-UHN) , Toronto , ON , Canada.
3
c Audiology and Speech-Language Pathology Program , University of Ottawa , Ottawa , Canada.
4
d Toronto Western Hospital-University Health Network (TWH-UHN) , Toronto , ON , Canada.
5
j Department of Medicine (Neurology) , University of Toronto , Toronto , Canada.
6
e Sunnybrook Health Sciences Centre , Toronto , ON , Canada.
7
f Institute of Medical Science, University of Toronto , Toronto , ON , Canada.
8
g L.C. Campbell Cognitive Neurology Research Unit , Sunnybrook Health Sciences Centre , Toronto , ON , Canada.
9
h Brain Sciences Research Program , Sunnybrook Research Institute , Toronto , ON , Canada.
10
i Rotman Research Institute-Baycrest Centre , Toronto , ON , Canada.
11
k Heart and Stroke Foundation , Partnership for Stroke Recovery , Ontario , ON , Canada.

Abstract

Using an anagram task, we investigated longitudinal syntactic production by individuals with semantic variant primary progressive aphasia (svPPA) and non-fluent variant PPA (nfvPPA), compared to controls. The accuracy of the production of active and passive, and reversible and non-reversible sentences, as well as of wh- questions was compared across the three groups. Results showed a different pattern of syntactic impairment across the two patient groups. The nfvPPA group showed difficulty with wh- questions at Time 1 and impairment with the passive structure approximately one year later, at Time 2. Surprisingly, the svPPA group also showed difficulty with wh- questions from Time 1, but still no difficulty on passive sentences, two years later, at Time 3. Neither group had difficulty with reversibility. The results of the nfvPPA patients were as expected, and the results of the svPPA patients suggest that this group may exhibit a greater syntactic impairment than is typically recognized.

KEYWORDS:

Syntactic production; constrained anagram task; non-fluent variant primary progressive aphasia; primary progressive aphasia; semantic variant primary progressive aphasia

PMID:
27341394
DOI:
10.1080/02643294.2016.1179179
[Indexed for MEDLINE]

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