Abstract
Stem cell membrane-coated nanogels can effectively evade clearance of the immune system, enhance the tumor targeting properties and antitumor chemotherapy efficacy of gelatin nanogels loaded doxorubicin in mice.
Keywords:
biomimetic nanoparticles; stem cell membrane; targeted drug delivery; tumor therapy.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
MeSH terms
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Animals
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Cell Membrane / chemistry*
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Doxorubicin / administration & dosage
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Doxorubicin / therapeutic use
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Drug Carriers / chemistry*
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Drug Delivery Systems / methods
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Female
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HeLa Cells
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Humans
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Mice
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Nanogels
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Nanoparticles / chemistry
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Polyethylene Glycols / chemistry*
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Polyethyleneimine / chemistry*
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Stem Cells / chemistry*
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Uterine Cervical Neoplasms / drug therapy
Substances
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Drug Carriers
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Nanogels
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polyethylene glycol polyethyleneimine nanogel
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Polyethylene Glycols
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Doxorubicin
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Polyethyleneimine