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Glob Pediatr Health. 2014 Oct 9;1:2333794X14553625. doi: 10.1177/2333794X14553625. eCollection 2014.

Improving the Rate of Sufficient Sweat Collected in Infants Referred for Sweat Testing in Michigan.

Author information

1
Children's Hospital of Michigan Cystic Fibrosis Center, Detroit, MI, USA.
2
Michigan Department of Community Health, Lansing, MI, USA.
3
Michigan State University Cystic Fibrosis Center, East Lansing, MI, USA.
4
Helen DeVos Children's Hospital Cystic Fibrosis Center, Grand Rapids, MI, USA.
5
University of Michigan Cystic Fibrosis Center, Ann Arbor, MI, USA.

Abstract

OBJECTIVE:

Sweat collected for testing should have quantity not sufficient (QNS) rate of ≤10% in babies ≤3 months of age. Michigan (MI) cystic fibrosis (CF) centers' QNS rates were 12% to 25% in 2009. This project was initiated to reduce sweat QNS rates in MI. Methods/Steps. (a) Each center's sweat testing procedures were reviewed by a consultant. (b) Each center received a report with recommendations to improve QNS rates. (c) Technicians visited other participating centers to observe their procedures.

RESULTS:

A total of 778 infants were identified as positive via CF newborn screening over a 2-year period. The mean age at time of sweat test was 23.2 days (SD ± 13.0 days). The overall QNS percent decreased from 14.4% to 9.5% (P = .04) during the study.

CONCLUSION:

This project and teamwork approach led to a decrease of sweat test QNS rates, opportunities to solve a common problem, and improved quality of care.

KEYWORDS:

general pediatrics; genetics; infectious diseases; neonatology; pulmonology

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