Format

Send to

Choose Destination
See comment in PubMed Commons below
J Clin Epidemiol. 1989;42(5):473-6.

The alternative hypothesis: one-sided or two-sided?

Author information

1
Parke-Davis Research Division, Warner-Lambert Company, Ann Arbor, MI 48105.

Abstract

The appropriateness of a one-sided alternative hypothesis rather than the more conservative, boiler-plate, two-sided hypothesis is discussed and examples provided. It is concluded that confirmatory efficacy clinical trials of pharmaceutical compounds should always be viewed within the one-sided alternative hypothesis testing framework.

Comment in

PMID:
2732775
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center