Send to

Choose Destination
Biosci Biotechnol Biochem. 2016 Oct;80(10):1995-2000. doi: 10.1080/09168451.2016.1194183. Epub 2016 Jun 13.

Resistant starch reduces colonic and urinary p-cresol in rats fed a tyrosine-supplemented diet, whereas konjac mannan does not.

Author information

a The United Graduate School of Agricultural Science , Gifu University , Gifu , Japan.
b Faculty of Applied Biological Sciences , Gifu University , Gifu , Japan.
c The Graduate School of Applied Biological Sciences , Gifu University , Gifu , Japan.


The effect of resistant starch (RS) and konjac mannan (KM) to maintain and improve the large intestinal environment was compared. Wistar SPF rats were fed the following diets for 4 weeks: negative control diet (C diet), tyrosine-supplemented positive control diet (T diet), and luminacoid supplemented diets containing either high-molecular konjac mannan A (KMAT diet), low-molecular konjac mannan B (KMBT diet), high-amylose cornstarch (HAST diet), or heat-moisture-treated starch (HMTST diet). The luminacoid-fed group had an increased content of short-chain fatty acids in the cecum. HAS caused a significant decrease in p-cresol content in the cecum, whereas KM did not. Urinary p-cresol was reduced in the HAST group compared with the T group, but not the KM fed groups. Deterioration in the large intestinal environment was only improved completely in the HAST and HMTST groups, suggesting that RS is considerably more effective than KM in maintaining the large intestinal environment.


konjac mannan; p-cresol; phenol; resistant starch; short-chain fatty acid

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center