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Mycoses. 2016 Aug;59(8):535-8. doi: 10.1111/myc.12519. Epub 2016 Jun 13.

Identification and typing of the emerging pathogen Candida auris by matrix-assisted laser desorption ionisation time of flight mass spectrometry.

Author information

1
R&D Microbiology, bioMérieux, La Balme les Grottes, France.
2
R&D Biomathematics, bioMérieux, Grenoble, France.
3
Laboratório Especial de Micologia, Escola Paulista de Medicina, UNIFESP, São Paulo, Brazil.
4
Department of Medical Microbiology and Infectious Diseases, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
5
Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
6
Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.

Abstract

Candida auris is an emerging antifungal resistant yeast species causing nosocomial and invasive infections, emphasising the need of improved diagnostics and epidemiological typing methods. We show that MALDI-TOF VITEK-MS followed by amplified length polymorphisms allows for accurate species identification and subsequent epidemiological characterisation of strains encountered during potential outbreaks.

KEYWORDS:

Candida auris; MS VITEK; amplified fragment length polymorphism; matrix-assisted laser desorption ionisation-time of flight mass spectrometry

PMID:
27292939
DOI:
10.1111/myc.12519
[Indexed for MEDLINE]

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