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Rev Psiquiatr Salud Ment. 2016 Oct - Dec;9(4):219-227. doi: 10.1016/j.rpsm.2016.04.003. Epub 2016 Jun 10.

Differential blood-based biomarkers of psychopathological dimensions of schizophrenia.

[Article in English, Spanish]

Author information

1
Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Oviedo, Asturias, España; Instituto de Neurociencias del Principado de Asturias (INEUROPA), Asturias, España; Área de Psiquiatría, Universidad de Oviedo, Asturias, España. Electronic address: lettti@gmail.com.
2
Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Oviedo, Asturias, España; Instituto de Neurociencias del Principado de Asturias (INEUROPA), Asturias, España; Área de Psiquiatría, Universidad de Oviedo, Asturias, España; Servicio de Salud del Principado de Asturias (SESPA), Asturias, España.
3
Área de Psiquiatría, Universidad de Oviedo, Asturias, España; Servicio de Salud del Principado de Asturias (SESPA), Asturias, España.
4
Área de Psiquiatría, Universidad de Oviedo, Asturias, España.

Abstract

Symptomatology of schizophrenia is heterogeneous, there is not any pathognomonic symptom. Moreover, the diagnosis is difficult, since it is based on subjective information, instead of markers. The purpose of this study is to provide a review of the current status of blood-based biomarkers of psychopathological dimensions of schizophrenia. Inflammatory, hormonal or metabolic dysfunctions have been identified in patients with schizophrenia and it has attempted to establish biomarkers responsible for these dysfunctions. The identification of these biomarkers could contribute to the diagnosis and treatment of schizophrenia.

KEYWORDS:

Biomarcadores; Biomarkers; Cognición; Cognition; Esquizofrenia; Negative symptoms; Positive symptoms; Schizophrenia; Síntomas negativos; Síntomas positivos

PMID:
27291830
DOI:
10.1016/j.rpsm.2016.04.003
[Indexed for MEDLINE]

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