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Am J Clin Oncol. 1989 Jun;12(3):190-4.

Comprehensive lymphatic irradiation for stage II-III non-Hodgkin's lymphoma.

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  • 1Department of Radiation Oncology, University of Florida College of Medicine, Gainesville.


Thirteen patients with stage II-III non-Hodgkin's lymphoma (NHL) and one patient with minimal marrow involvement were selected for treatment between 1964 and 1986 with moderate-dose comprehensive lymphatic irradiation (CLI). This approach has been well tolerated and has produced relapse-free and overall survival rates at 10 years of 60 and 66%, respectively. Salvage therapy for failure following CLI has been possible. CLI produces results comparable to any achieved with combined modality therapy, offers less acute and late toxicity, and requires only 3-4 months for completion.

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