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Clin Implant Dent Relat Res. 2017 Feb;19(1):38-45. doi: 10.1111/cid.12429. Epub 2016 Jun 9.

Horizontal Ridge Augmentation using GBR with a Native Collagen Membrane and 1:1 Ratio of Particulated Xenograft and Autologous Bone: A 1-Year Prospective Clinical Study.

Author information

1
Assistant Professor, University of Sassari, Italy.
2
associated professor, Loma Linda University, CA, USA.
3
Assistant professor, Loma Linda University, CA, USA; Urban Regeneration Institute, Budapest, Hungary.
4
Independent Researcher in Rome, Rome, Italy.
5
private practice in Sassari, Italy.
6
Lecturer, University of Sassari, Italy.

Abstract

AIM:

To clinically and radiographically evaluate bone regeneration of severe horizontal bone defects.

MATERIALS AND METHODS:

This study was designed as a single cohort, prospective clinical trial. Partially or fully edentulous patients, having less then 4 mm of residual horizontal bone width were selected and consecutively treated with resorbable collagen membranes and a 1:1 mixture of particulated anorganic bovine bone and autogenous bone, 7 months before implant placement. Tapered body implants were inserted and loaded 3 to 6 months later with a screw retained crown or bridge. Outcomes were: implant survival rate, any biological and prosthetic complications, horizontal alveolar bone dimensional changes measured on cone beam computed tomography (CBCT) taken at baseline and at implant insertion, peri-implant marginal bone level changes measured on periapical radiographs, plaque index (PI), and bleeding on probing index (BoP).

RESULTS:

Eighteen consecutive patients (11 females, 7 males) with a mean age of 56.8 years (range 24-78) and 22 treated sites received 55 regular platform implants. No patient dropped-out and no implants failed during the entire follow-up, resulting in a cumulative implant survival rate of 100%. No prosthetic or biological complications were recorded. Supraimposition of pre- and 7-month post-operative CBCT scans revealed an average horizontal bone gain of 5.03 ± 2.15 mm (95% CI: 4.13-5.92 mm). One year after final prosthesis delivery, mean marginal bone loss was 1.03 ± 0.21 mm (95% CI 0.83-1.17 mm). PI was 11.1% and BoP was 5.6%.

CONCLUSION:

Within the limitation of the present study, high implant survival rate and high average bone augmentation seem to validate the use of collagen resorbable membranes with a 1:1 mixture of particulated anorganic bovine bone and autogenous bone, for the reconstruction of severe horizontal ridge defects.

KEYWORDS:

alveolar ridge reconstruction; atrophy; autologous bone; bone augmentation; bone defects; bone regeneration; bone substitutes; xenograft

PMID:
27283920
DOI:
10.1111/cid.12429
[Indexed for MEDLINE]

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