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J Evid Based Complementary Altern Med. 2016 Oct;21(4):NP103-9. doi: 10.1177/2156587216652572. Epub 2016 Jun 5.

Expectancy Effect in Three Mind-Body Clinical Trials.

Author information

1
National College of Natural Medicine, Portland, OR, USA matthewhicks12@gmail.com.
2
National College of Natural Medicine, Portland, OR, USA.
3
National College of Natural Medicine, Portland, OR, USA Oregon Health & Science University, Portland, OR, USA.

Abstract

Expectancy, arguably the prime component of the placebo effect, has been shown to significantly modify the effects of many treatments. Furthermore, various forms of mind-body interventions have demonstrated effective improvements in outcomes. The aim of this study was to examine the relationship between pretreatment expectations and symptom reduction in a secondary analysis of 3 mind-body intervention programs. An adjusted correlation and regression analysis compared data from a 6-question expectancy questionnaire to a self-reported clinical impression of change score. Only 1 of the 6 expectancy questions in 1 of the 3 studies reached significance (B = 0.087; P = .025). The combined data from all 3 studies did not reveal significant expectancy effects. The positive effects of mindfulness meditation appear to be independent of an expectancy effect.

KEYWORDS:

expectancy; meditation; mind-body; mindfulness-based stress reduction

PMID:
27269794
DOI:
10.1177/2156587216652572
[Indexed for MEDLINE]

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